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In this special film, Evans visits the V&A and Windsor Castle to reveal how Raphael made the cartoons which were used to make tapestries by specialist weavers in Brussels and how they come to be at the V&A. Meanwhile, in Rome, Vatican Museum Curator, Professor Arnold Nesselrath explains how Raphael applied his 'universal genius' to sculpture, architecture and tapestry as well as painting.

At the film's climax, the two curators meet in the Sistine Chapel to witness a hanging of the Raphael tapestries in 'the greatest room in art' . This rare event took place in July 2010 as the prelude to the autumn's historic V&A exhibition.